Diabetes Has Five Classifications, Researchers Say

Diabetes insulin-syringe

Diabetes insulin-syringe

"Both type 1 and type 2 diabetes are serious conditions that can lead to devastating complications such as amputation, blindness, kidney disease, stroke and heart disease if people don't receive a timely diagnosis and begin receiving the right care". Notably, the study's parameters were not able to confirm different causes of the five different types.

Around a fifth of all participants were classified in cluster 4.

Finally, the Malmö Diet and Cancer CardioVascular Arm (MDC-CVA) study included 3,330 people randomly selected from the larger Malmö Diet and Cancer study.

They also looked at various patient characteristics, complication rates - such as kidney and diabetic eye problems - and use of medications.

The charity revealed this week that the number of people diagnosed with Diabetes in the United Kingdom has more than doubled in the past 20 years to nearly 3.7 million. Essentially the same as type 1.

"This is the first step towards personalised treatment of diabetes", said Leif Groop, Professor at Lund University in Sweden.

There were patients whose cells also stopped producing insulin, but not due to their immune system; they were often young and in otherwise good shape.

Future research is also needed to test and refine the 5 types to include biomarkers, genotypes, genetic risk scores, blood pressure and blood lipids. Current diagnostics and classification of diabetes are insufficient and unable to predict future complications or choice of treatment'. Diabetes Canada feels that the investment made should be more as the supplies alone can reach to $300 per month.

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Diabetes is now divided into type 1 diabetes (approximately 10%), type 2 diabetes (85-90%) and several less common diseases like latent autoimmune diabetes in adults (LADA), maturity onset diabetes of the young (MODY) and secondary diabetes. By analysing 13,270 diabetics, . the study identified three...

Severe insulin-deficient diabetes (SIDD): GADA-negative but otherwise similar to SAID. The other mild form (cluster 4/ mild obesity-related diabetes (MOD)), was seen mainly in obese patients who fall ill at a young age and affected 18-23% of patients. Identified in 22% of the people in ANDIS.

Cluster 5 are patients with mild, age-related diabetes who developed symptoms at a late age, hence diabetes was not as severe. The most common cluster.

How did the researchers interpret the results?

The two "types" of the disease are not precise enough - and the adult-onset varieties of the disease should be split into five distinct categories, according to the paper in The Lancet Diabetes and Endocrinology. Up to 6 to 15 per cent patients had Type I diabetes.

Shock new figures show that a further 2,000 people were diagnosed with the condition in 2017, bringing the numbers of people in the county diagnosed with diabetes to almost 42,000.

The new substratification might help to tailor and target early treatment to those who would benefit most.

However, experts believe that changes to diabetes treatment may not be available anytime soon. The clusters and associated complications will need to be verified in other populations, including other ethnicities that may have a different risk of diabetes, such as Asian populations.

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